cannabis, RA journal
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RA, a Progressive Disease

I have seronegative rheumatoid arthritis. That means I have more issues with inflammation and less joint damage that a person with seropositive rheumatoid arthritis. My rheumatologist sometimes thinks they must be two different diseases.

Once diagnosed both are given the same treatment. I was on methotrexate for seven years. It helped about fifty percent. Biologics helped anywhere from twenty to fifty percent. The combination made life bearable. Methotrexate had been a difficult drug with the side effects of nausea and diarrhea. They passed. With the injectable version of methotrexate, the side effects disappeared.

I have a history of breast cancer that required surgery and radiation. It left my breast tissue with poor circulation. I developed methotrexate black box complication number thirteen, soft tissue necrosis. It took ten months to heal and included surgery. Absolutely no more methotrexate, or it would happen again. So I lost my fifty percent relief. I was lucky to get twenty percent relief with the biologics. I have been through most of them. The TNF inhibitors can cause cancer and the newer JAK inhibitors can cause cancer. Not a good choice as I have had five different cancers.

I am on Kevzara. Good for twenty percent. Low dose methylprednisolone. More of it for flares. Low dose cannabis gummies. No more than 2.5mg at a time. I use a combination of THC, CBD, CBG and CBN. A combination of CBD and THC work better than any slinge element. Cannabis helps me by relieving some of the inflammation I have.

Flares are still debilitating. Cannabis usually takes the edge off inflammation. Lately, I have had more problems. More pain in the multiple involved joints. More inflammation. I take extra cannabis and I find tramadol helps. It is easy to get discouraged.

I believe writing a romantic adventure helped take my mind off how relentless my symptoms are on a daily basis. Baseball season is done. Maybe it is time to write another book.


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