All posts filed under: inflammatory arthritis diseases

Mary Mann inflammatory arhtritis

Meet Ankylosing Spondylitis (AS)

  Spondylo means vertebrae or bones in your back. So, you can see that AS affects the spine. With the progression of disease, the vertebral joints fuse causing the spine to be stiff. AS affects the  areas where the joint capsules, tendons and ligaments attach to the bones. Pain and swelling occur  along these “hotspots”. The lower back, the sacroiliac joints,  the cervical spine, pelvic bones, the rib joints and the heel. Classic AS involvement. Many other joints can be involved. The joints of the hip, shoulder, and knee are commonly involved. Involvement of fingers, toes, wrists and jaw, although possible, is not common. It is a disease of younger people (teen-40s) usually. It is common in men, but science is learning that women have AS frequently, too. It is a major cause of low back pain. It is an inherited disease. There are many genes involve. The gene HLA-B27 is present in 90% of those who have AS. As in many cases an environmental trigger like an infection activates the genes involved. AS belongs …